Lack of narrow therapeutic index awareness leading to increased risk of acute phenytoin toxicity in a child with traumatic brain injury
نویسندگان
چکیده
Phenytoin is a commonly prescribed antiepileptic medication in the pediatric age group for multiple indications. It has very narrow therapeutic range with well known side-effects. A careful dose dispensing of utmost importance while administering medications index especially groups variable weight bands. Multiple dosage formulations like tablets/syrups varying strength ranging from 30-300mg are available market just small difference color coding on labels making it prone to iatrogenic errors leading toxicity.
منابع مشابه
Effects of minocycline on neurological outcomes in patients with acute traumatic brain injury: a pilot study
Traumatic brain injury (TBI) is a public health problem worldwide. Secondary damage of brain injury begins within a few minutes after the trauma and can last a long time. It can be reversible, unlike primary injury. Therefore, therapeutic intervention can be used. The aims of this study were to assess the effects of minocycline on neurological function and serum S100B protein and neuron-specifi...
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Traumatic brain injury (TBI) is a public health problem worldwide. Secondary damage of brain injury begins within a few minutes after the trauma and can last a long time. It can be reversible, unlike primary injury. Therefore, therapeutic intervention can be used. The aims of this study were to assess the effects of minocycline on neurological function and serum S100B protein and neuron-specifi...
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ژورنال
عنوان ژورنال: Open journal of pediatrics and child health
سال: 2021
ISSN: ['2640-7612']
DOI: https://doi.org/10.17352/ojpch.000032